This Presidential Action, issued under the authority granted by the International Emergency Economic Powers Act (IEEPA) and the National Emergencies Act (NEA), builds upon the national emergency declared in Executive Order 14380 concerning the policies and actions of the Government of Cuba.

The order directs the Secretary of State and Secretary of the Treasury to block the property and interests in property of foreign persons determined to be involved in operating within key destabilizing sectors of the Cuban economy, engaging in serious human rights abuses, or corruption.

Furthermore, it suspends the entry of such designated aliens into the United States and authorizes sanctions, including blocking U.S.-held assets, against foreign financial institutions that facilitate transactions for blocked persons.

This document details presidential actions regarding nominations and withdrawals sent to the Senate for consideration.

It lists eleven individuals nominated for positions including Ambassador to Australia, Deputy Director of the Office of Management and Budget, Assistant Secretaries across various departments (Health and Human Services, Treasury, State, Commerce), an Inspector General for HUD, and two United States Circuit Judges.

Additionally, the document formally communicates the withdrawal of three previous nominations related to the Department of Labor, the Equal Employment Opportunity Commission, the Cybersecurity and Infrastructure Security Agency, and the Director of the National Park Service.

This document lists several individuals nominated by the President and sent to the Senate for confirmation to various high-level positions within the U.S. government.

The nominations cover roles including the Director of the Peace Corps, Ambassadors, the Inspector General of the Department of Justice, U.S. Attorney, Assistant Secretaries in the Air Force, the Director of the National Reconnaissance Office, the Chairman of the Council of Economic Advisers, the Director of the CDC, and an Assistant Secretary for Veterans Affairs.

The President issued a memorandum exempting the United States Air Force's jet fighter training operations located in Idaho, Oregon, and Nevada from Federal, state, and local requirements concerning water pollution control and abatement for a one-year period, specifically from April 20, 2026, to April 20, 2027.

This action is taken pursuant to the Federal Water Pollution Control Act, based on the determination that these exemptions are in the paramount interest of the United States, particularly in relation to ongoing litigation regarding these training activities, although specific sections of the Act (33 U.S.C. 1316 and 1317) remain in effect.

This Presidential Action establishes a policy to accelerate the research, drug approval process, and access to innovative treatments, specifically psychedelic drugs like ibogaine compounds, for Americans suffering from serious mental illnesses such as major depressive disorder and substance abuse disorder, citing persistent high rates of suicide and inadequate results from standard therapies.

The order directs the FDA to prioritize review via National Priority Vouchers, mandates the establishment of access pathways via the Right to Try Act, allocates HHS funding for State partnerships, directs collaboration between HHS, FDA, and VA for data sharing, and requires the Attorney General to expedite rescheduling reviews for compounds that successfully complete Phase 3 clinical trials.

The President issued a Presidential Permit, exercising authority vested in the office, to Enbridge Energy, Limited Partnership, a Canadian-owned subsidiary, to operate and maintain three existing pipeline Border facilities in Pembina County, North Dakota, for transporting crude oil and various petroleum products across the U.S.-Canada border.

This permit supersedes a previous permit from 1991 and establishes several conditions, including subjecting the facilities to all applicable laws and regulations, mandating permittee responsibility for maintenance and liability indemnity, granting the U.S. the right to take possession for national security purposes, and requiring removal of the facilities upon permit termination unless otherwise directed.

The President granted a Presidential Permit to Enbridge Energy, Limited Partnership, an indirect Canadian subsidiary, authorizing the operation and maintenance of specific existing pipeline Border facilities near Neche, North Dakota, for the cross-border transport of crude oil and various petroleum products, excluding natural gas.

This permit supersedes a previous permit issued in 1998 and establishes a detailed framework of conditions, including adherence to all applicable Federal, State, and local laws, requiring regular government inspection access, imposing strict rules on facility changes or ownership transfers, and reserving the right for the U.S. government to take possession of the facilities for national security purposes.

The President issued a Presidential Permit authorizing Enbridge Energy, Limited Partnership, a subsidiary of a Canadian corporation, to operate and maintain its existing pipeline Border facilities in Pembina County, North Dakota, for the purpose of transporting crude oil and petroleum products between the United States and Canada.

This permit supersedes a previous 1994 permit and outlines nine specific conditions, including subjecting the facilities to federal, state, and local regulation, requiring the permittee to remain responsible for maintenance and indemnification, and reserving the President's right to take possession of the facilities for national security reasons.